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This substance prolongs life expectancy, prevents age-related brain mitochondrial dysfunction, promotes mitophagy, and reverses heart disease. But what is spermidine and why should it be included in your diet?

This article will discuss some of the health benefits of spermidine and how to get more of it in your diet. Whether you are looking for a way to make your sperm count higher or want to boost the health of your eggs, spermidine is an excellent supplement to add to your diet.

spermidine prolongs lifespan

In animal studies, spermidine has been shown to increase lifespan and protect against liver fibrosis and hepatocellular carcinoma. The compound may also improve resistance to stress and age-related diseases.


This compound is also found naturally in many food and agricultural products, including eggs, milk, corn, and whole grains buy spermidine. For these reasons, spermidine is a promising candidate for dietary supplements.

For now, however, studies are necessary to determine exactly how much it contributes to longevity.

It prevents age-related brain mitochondrial dysfunction

Research shows that spermidine can prevent age-related brain mitochondrial malfunction and memory loss.

It works by increasing ATP production, suppressing apoptosis, and promoting autophagy, the process that removes floundering mitochondria. However, this drug has other limitations.

Because it may have side effects, such as toxicity, it is important to take a dose that is safe for your health.

It promotes mitophagy

Researchers have found that the peptide spermidine promotes mitophagy in nematodes and has anti-aging effects.

It is also able to protect neuronal cells from oxidative stress and is beneficial for the treatment of age-related diseases.

The peptide is believed to have protective effects against several neurodegenerative disorders, including Alzheimer’s disease, Parkinson’s disease, and motor neuron disease.

It reverses heart disease

A recent study found that a drug known as spermidine could effectively reverse heart disease. The drug has the ability to mimic caloric restriction and protect the circulatory system from damage.

It also improves cardiac function and prevents hypertrophy. It has also been shown to delay the onset of hypertension in rats. It is currently being tested on humans and may be a useful tool in the fight against cardiovascular disease.

It prevents liver fibrosis

Researchers have shown that consuming spermidine prevents liver fibrosis. Its mechanisms of action are to enhance the stability of MAP1S proteins and activate autophagy flux.

As a result, it is an effective treatment for HCC and can be safely consumed by patients with chronic liver disease. However, it is important to note that the benefits of spermidine are dependent on the presence of MAP1S. MAP1S is responsible for autophagy, a crucial step in the progression of liver fibrosis.

It reduces wrinkles

One of the most common signs of aging is the appearance of wrinkles. However, spermidine may be the solution to your wrinkle problem. Spermidine is an organic polyamine that has multiple metabolic functions. It was isolated from the male sperm.

It is produced by breaking down spermine (the precursor to spermidine). It has been shown to promote autophagy, which is a process of recycling damaged organelles and cleansing the body of toxic waste. This process can be accelerated by physical exercise and stress.

It improves memory

Recent research shows that spermidine can improve memory. It was found that high levels of spermidine are linked with better memory in older adults.

In addition, spermidine can improve the performance of neural differentiation in vitro, which may help preserve the memory of reconsolidated memories.

Although further research is needed to confirm these findings, these studies have demonstrated that spermidine has the potential to improve memory. However, these findings need to be further investigated before they can be used in clinical settings.

It protects against artery-blocking plaques

A new study shows that a molecule called spermidine can inhibit the formation of artery-blocking plaques. Spermidine works by up-regulating the SIRT1 gene, which is responsible for vascular calcification.

These findings suggest that spermidine can be a promising therapeutic treatment for vascular calcification. This study also suggests that spermidine may be beneficial in CKD.

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